Fmoc-β-Ala-Thr(tBu)-OH Dipeptide Building Block For SPPS

Used in Solid-Phase Peptide Synthesis as a dipeptide building block:

• Efficient incorporation of β-Ala–Thr fragment

• Reduces coupling steps

• Compatible with Fmoc strategy

Threonine provides:

• Hydroxyl group (after deprotection)

• Hydrogen bonding capability

• Increased polarity

Used in:

• bioactive peptides

• enzyme substrates

• phosphorylation-related studies

• Protects hydroxyl group during synthesis

• Prevents side reactions

• Easily removed under acidic conditions (TFA)

• Improves conformational flexibility

• Reduces steric hindrance

• Optimizes peptide spatial arrangement